There is not problem to use OSC for focus or plate solving, just more difficult due to the reduced signal, so its matter of your settings.
OSC camera have resolution different from normal calculation due to the bayer matrix … if you want to use AllSkyPlateSolver you must edit the right focal lenght in Voyager to avoid long time on resolution or timeout, just few unit of difference in focal lenght mean problem on solving. You must solve before and reading the exact focal lenght and save it.
For plate solving better to not use All Sky Plate Solver is not really fast, use it for Blind.
2x2 bin remove the bayer matrix so you fastening the process and have better data to use for plate solving (no matrix with black row col)
Remember to download the right index for ASPS related to your setup.
All the best